Risks Involved With the Use of Piracetam: Is It Safe for you?


Even though Piracetam was the very first nootropic ever synthesized, it still remains as one of the preferred smart drugs for cognitive enhancement. This nootropic compound was developed by Hungarian chemist, Dr. Corneliu Giurgia in 1964 while working for UCB, a multi-national pharmaceutical company based in Brussels, Belgium. He was amazed by the positive effects of Piracetam on memory, learning abilities, concentration, and other cognitive functions that he coined the term “nootropic” to refer to such substances.

Piracetam is also one of the most researched nootropics and its ability to improve cognitive functions has been well-documented. Today, nootropic users still consider it as one of the best smart drugs around. One of the main reasons why it remains as one of the favorite smart drugs is because of its low-toxicity profile, which makes it one of the safest nootropics to use. Studies show that it is safe to use Piracetam even in extremely high doses.

Piracetam RisksIt would be wrong however, to think that since Piracetam is generally deemed as safe, that its supplementation involve very little risk. As with any other supplements, it would be wise to consider the risks involved with the use of Piracetam before starting with its supplementation. As a precautionary measure, there are a few important matters that you should consider if you are planning to use this nootropic.


Contrary to the pervasive belief that anyone can use Piracetam, there are a number of cases wherein its supplementation is not advised. There are even some cases where the use of Piracetam can pose a serious health risk. The following are some of the issues that may not make Piracetam a suitable nootropic supplement for you.

  • Allergies. There are documented cases wherein individuals were observed to have moderate to extreme allergic reaction to this racetam. You may have consult with a medical professional if you wish to figure out if you are allergic to this smart drug safely.
  • Liver issues. Piracetam may worsen existing conditions of the liver, which is why it may not be safe for anyone who has serious liver problems.
  • Kidney issues. If you have seriously impaired kidney functions, Piracetam supplementation will not be advisable as it can cause health complications. Piracetam is exclusively excreted via the kidneys, which is why extra precaution is warranted in individuals with kidney problems.
  • Brain issues. Piracetam may be used to help someone recover from some types of brain injury. However it may actually have detrimental effects if the injury involves cerebral hemorrhaging. Those who have suffered a brain hemorrhage should refrain from taking Piracetam.
  • Age issues. The use of Piracetam may not be suitable for individuals 16 years old and below. It is believed that the brain is still naturally growing neurons during this stage and using Piracetam may interfere or upset this process.

While Piracetam is prescribed as treatment and management for a wide range of neurodegenerative conditions, its supplementation is not advisable for Huntington’s chorea. Experts believe that that Piracetam may worsen the symptoms and speed up the progression of the disease. Pregnant and lactating women should postpone supplementation until after giving birth and breastfeeding.


As of this publishing, there is only one case wherein Piracetam was observed to interact with a drug. This smart drug was observed to cause confusion, insomnia, and irritability when taken together with thyroid extracts.

Piracetam is believed to have a few side effects. Among the commonly reported side effects include headaches, dizziness, upset stomach, anxiety, irritability, disturbed sleep patterns, nausea, vomiting, and diarrhea. It has also been known to cause, albeit rarely, tremors, vertigo, and sexual stimulation.

To be on the safe side, the best way to go about beginning a regimen Piracetam or any other supplement, is to consult your doctor about your supplementation plans.


  1. Elizabeth Taylor says:

    Hi, i hope i get a reaponse to my question:) Im curious about racetam use in dialysis patients. Of course, my father woukd need to consukt with his dr, im just curious if anyone here knows if there are issues with it. His kidneys only funvtion at like 5%, but hes on dialysis, which incase anyone isnt aware of how it works, iys a special solution used (in his case) once a day (obernight/different cycles/about 7hiurs total) so the fluids do the job of the kidneys and flush the toxins from his beody when he drains it. I totally understand how someone who is suffering from failing kidneys, would most likely be recommended against using rice at times, however, he is on dialysis and is using the dialysis system and replacement of his kidneys, do you know what I mean? So it’s not as if his kidneys are functioning so badly, that he would be at risk for harming himself, as it’s already Way Beyond that and and I’ll ternative method is being used 2 flush the system from toxins. He’s been on this for about three and a half years now and is on the kidney transplant wait list, but I’ve noticed his memory slipping lately, he’s like 77 so I know some of this is normal, however, I still like to know if you could supplement with something from the Reisterstown family safely so old, I was just curious if anybody here knows already rather this would be a problem or not before I speak to his Dr. Im just gathering information… Thank you for your time.

  2. Livia Manolescu says:


    For your information and in the memory of Dr. Corneliu Giurgia, you should offer correct information about his origin. He is born in Bucharest, the capital of Romania, his nationality is Romanian, his name is 100% Romanian and he graduated the Institute of Medicine and Pharmacy in Bucharest, Romania.

    Hope you will offer us right information.

    Livia Manolescu

    • That’s corrct, Dr. Corneliu E. Giurgea (Romanian scientist) is known as the godfather of brain pharmacology
      and cognitive performance research science. In 1964 he synthesized piracetam, a compound shown to boost memory, learning, creativity, verbal fluency, and brain circulation (for UCB). Oryginal UCB piracetam here:
      https://nootropicsjet.com/product/piracetam-geratam-60x1200mg/ . He also first coined the term “nootropic”.

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