Semax is one of the very few drugs that are specifically prescribed for cognitive enhancement. While it is also being prescribed for a variety of neurological and psychological conditions, its effects are aimed at improving the cognitive processes of the brain, and these include memory enhancement, logical reasoning, learning skills, and communication skills.
Developed in the former Soviet Union in the early 1980s, its development was initially focused on creating an effective treatment brain damage caused by stroke. As the development of Semax progressed, its strong potential as a cognitive enhancer became so apparent that its research team focused their efforts towards this direction. These days, Semax is widely recognized as one of the world’s most potent and most effective nootropic.
Semax is a peptide with seven distinct molecules and a synthetic derivative of corticotropin. It is most active in the central nervous system where it works on the most important neurotransmitters in the brain, particularly the most important ones that contribute to the cognitive processes in the brain like acetylcholine, serotonin, dopamine, and norepinephrine. Semax also stimulates the glutamate receptors in the CNS and gives added energy to the neurons.
Apart from being a nootropic, this drug is also prescribed in Russia and Ukraine to speed up the recovery of ischemic stroke victims, to help people suffering from cognitive decline, to treat amnesic patients, and even to treat seemingly unrelated medical conditions such as diseases of the optic nerve and ulcers.
The commercially available Semax comes in the form of nasal drop solution in 3ml bottles, which some often mistake as nasal spray solution. Semax, being a very potent nootropic drug, is available in two strengths. The Semax in blue packaging has a concentration of .1% and this variant is suggested for users who want the drug for cognitive enhancement. The red variant has 1% concentration and it is generally prescribed for the treatment of strokes. Users however, often progress to the red variant even just for the nootropic properties of Semax.
The potency of Semax as a nootropic is estimated to be around 1,000 more powerful than piracetam. This easily qualifies Semax in the same category as other powerful nootropics such as Noopept, sunifiram, and unifiram. Users of Semax emphasize that it cannot be compared to racetams because it has a smoother stim effect. The benefits of supplementing with Semax include enhanced mental clarity, improved logical reasoning, better memory retention and faster recall, acute mental focus, and increased verbal fluency.
The main problem that one will face when it comes to Semax supplementation is its price. For a 3ml bottle of the red variant, expect to cough out on the upwards of $190. On average, users tend to use up a bottle in as little as 10 days or even less. Another downside to Semax is that it is highly sensitive to heat that since there are very little suppliers of it in the US, you tend to wonder about its quality when it gets to you if you are lucky enough to find one for yourself.
- Very potent.
- Very effective.
- It has a very few side effects.
- It has a lot of side benefits.
- Very expensive.
- Suppliers are very limited.
- Sensitive to heat.
- Some may not be comfortable with nasal drop administration.
Given that Semax is very potent, its recommended dosages are quite small at about 2 drops for each nostril twice a day. This makes for approximately 60 dosages for the 3ml bottles. The catch to it, however, is that it is also advised that the frequency of dosing can also be on an “as needed” basis so users usually end up taking more than two dosages of Semax per day. The good news is that Semax has been deemed to be generally safe with a very low toxicity profile. To be on the safe side, it will be wise to consult with your doctor before you try out supplementing with Semax for cognitive enhancement.