Aniracetam is another nootropic in the racetam class that acts similarly to piracetam although it is considered to be stronger than piracetam in effects. This substance was created from the piracetam structure and has slightly different effects.
How does it work?
As with piracetam, aniracetam acts in a similar way by stimulating the acetylcholine receptors in the brain. Acetylcholine is a cognitive neurotransmitter and increasing the effects or function of acetylcholine and receptors is a function of many nootropics.
Aniracetam primarily works as a positive allosteric modulator of the acetylcholine receptors which means it acts to turn up the signal of acetylcholine rather than mimicking the effects of the neurotransmitter. By doing this, the nootropic can increase an acetylcholine activity and increase cognitive function.
This nootropic also has another function not related to acetylcholine receptors. It acts on another group of cognitive receptors. Glutamate is another learning and memory neurotransmitter and stimulation of these receptors also increases cognitive functions. Aniracetam acts in a similar way by stimulating glutamate receptors that act to improve learning and memory. These types of nootropics are known as ampakines.
So aniracetam works in two ways to improve cognitive functioning. First it improves the acetylcholine neurotransmitter function by increasing receptor activity. Secondly, it works as an ampakine by stimulating glutamate receptor activity. Both of these systems work together to provide increased cognitive function. For this reason, aniracetam is often combined or stacked with other racetams due to its unique cognitive profile.
Aniracetam is also believed to target specific serotonin receptors. Serotonin plays a large role in mood and behaviour regulation. For this reason, aniracetam has been thought to have some anxiety reducing effects as observed in animal studies. This effect may or may not be repeated in humans.
What to expect?
Not everyone who tries aniracetam will get an immediate benefit. Some people will experience an immediate increase in cognitive effects whereas others may take a while to experience the full range of benefits. Most people will get some noticeable results from aniracetam fairly quickly. It is a well-studied and proven nootropic that has been around for many years.
Aniracetam shares similarities and difference to its cousin, piracetam. People who have tried the piracetam may experience different effects from aniracetam even though they are very similar. This is due to the glutamate receptor effects of this nootropic. This nootropic is also superb to stack with other products, and it is somewhat affordable.
Generally, after taking aniracetam, one could experience immediate benefits. These benefits will likely become more apparent in highly demanding mental tasks. You may be able to remember things easier, or problem-solving skills may become more enhanced. Not everyone will experience similar benefits however this nootropic will probably show some improvement in several areas.
- Improved memory
- Enhanced learning
- Increased focus
- Improved problem solving skills
- Reduced anxiety
- Increased communication skills
Dosage & usage
Aniracetam is commonly bought in powder form. Unlike piracetam and oxiracetam, it cannot be mixed with water easily because it is fat soluble. Some people will put it into capsules while others will do the toss and wash method which entails putting the powder into your mouth and downing it with liquid. Contrary to popular belief, aniracetam does not need to be taken with a fat source, but the best results are when it is taken with food for absorption purposes.
Typical dosages of aniracetam range from 750mg-2000mg but more or less can be taken depending on the individual. It is not considered a substance that can be dangerous if taken in larger than recommended dosages however one should still be careful as side effects can manifest. Some users will take an attack dosage where 2-3 grams may be taken at a time, but this is not recommended for first-time users.
Aniracetam may be considered reasonably safe however one should still be very careful as side effects may manifest themselves. Side effects will usually relate to cholinergic over stimulation as choline; a precursor to acetylcholine gets taxed. This is thought to result in nasty headaches that can appear. It is believed that these headaches may be reduced when choline or an acetylcholine source is supplemented. This may or may not reduce these effects.
Other mood side effects can occur due to neurotransmitter; however aniracetam is thought to have less adverse effects in this area due to serotoninergic effects. Regardless, this supplement can still cause irritability and other mood side effects like depression. This is thought to be a result of a lowering of dopamine and serotonin levels due to increase in acetylcholine activity. These side effects may be reduced when a lower dosage is used, or mood supplements are brought into a stack.
Aniracetam is a great nootropic to stack. It has cholinergic and ampakine like properties that make it very well rounded. Most commonly it is stacked with piracetam or oxiracetam or both together. It is a very powerful supplement when added into a stack.
This supplement is also commonly combined with choline or acetylcholine supplements. Adding in choline or acetylcholine precursors may help to potentiate the effects it has on acetylcholine receptors.